3D CoSeedis™ consists of a unique agarose-based chip containing  an array of conical micro-wells. The particular and proprietary  topography of this arrangement allows the formation of spheroidal and  non-spheroidal cell aggregates in a highly-reproducible and consistent  manner. The conically shaped micro-wells within the array allow precise  determination of aggregate volume, hence cell growth. Furthermore, the  modular composition of the 3D CoSeedis™ system allows co-culturing of  feeder cells that are physically separated from the actual test cells  (distance co-culture). Consequently, this set-up is ideal for  the standardization of protocols under defined conditions.