Innovative photopatterning technology

Precisely control cell adhesion to isolate them or place them in reproducible conditions for standardized assays. Several of our users’ research works show the advantages of PRIMO contactless micropatterning at single cell, cell population, and high throughput levels: 

• Cell positioning within EM grids      for Cryo-ET (M. Toro-Nahuelpan et al., BioRxiv, 2019), 
• Airway smooth muscle cells patterning on gel for      contraction study (S. R. Polio et al., Sci. Rep., 2019).

One key advantage of PRIMO mask-less DMD-based photopatterning system is that it can perform grayscale photolithography on grayscale resists (collaboration with Physico-Chimie Curie UMR 168 and UMS-IPGG) and      therefore create complex 3D molds such as ramps, curving wells,      microfluidic chips for organ-on-a-chip applications. 

Inquire about the application note from this year’s MicroTas meeting...

PRIMO can also polymerize and photo-scission most commonly used hydrogels (A. Pasturel et al., BioRxiv, 2018) for applications such as 3D cell culture within micro-niches (C. Stoecklin et al., Adv. Biosys., 2018) or permeable      hydrogel membranes polymerization within microfluidic chips (J. Decock et al., Lab. Chip, 2018).