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Nanoparticle analysis with VideoDrop
Myriade is a French company, created in 2017, that develops nanoscale imaging technology. VideoDrop measures the size and concentration of nanoparticles such as viruses, phages and extracellular vesicles from a single drop, without labeling, using interferometric light microscopy.
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Supplied in the U.S. by nanoscaleLABS
Supplied in the U.S. by nanoscaleLABS
VideoDrop SC at a glance
5–10 µL
Sample volume, from a single drop.
80–500 nm
Size range for size and concentration.
About 1 minute
Per measurement, including loading, processing and cleaning.
1E8–1E10 particles/mL
Concentration range.
Models and technology
- VideoDrop SC Measures nanoparticle size and concentration. No labelling and non-denaturing, handles complex and viscous samples, and is 21 CFR Part 11 compliant. With no fluidics, cleaning is simple and clogging is avoided.
- VideoDrop SK Tracks how particle size changes over time, such as aggregation or complexation. It measures every 15 seconds for up to 4 hours, and is aimed at transfection workflow optimization in lentivirus and AAV bioproduction.
- Interferometric light microscopy A standard microscope is turned into an interferometer. An LED lights the sample, a high dynamic range camera records it, and algorithms track the interference patterns of each particle. Every particle is detected individually, which suits heterogeneous samples.
- Ease of use No calibration or parameters to adjust, so results are repeatable with no inter-operator bias. Minimal training and a fast learning curve make it suitable for multiple users.
Applications
- Lentiviral vectors
- Extracellular vesicles
- Lipid nanoparticles
- Transfection mix
- AAV bioproduction
- Aggregation and complexation
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nanoscaleLABS, LLC
Fairfax, VA 22030, USA
(703) 662-3276
info@nanoscalelabs.com